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Oxymetholone Long Cycle: How to Run Extended Anadrol Cycles Safely


πŸ’Š What is Oxymetholone?

Oxymetholone, commonly known as Anadrol, is one of the most potent oral anabolic steroids used in bodybuilding. It’s valued for its rapid and dramatic effects on muscle mass, strength, and endurance. Most users run Anadrol in short bursts due to its hepatotoxicity, but some advanced athletes experiment with longer cycles for extended gains.

This guide breaks down how to run an Oxymetholone long cycle effectivelyβ€”maximizing results while minimizing health risks.


πŸ” What Defines a “Long” Oxymetholone Cycle?

Typically, Anadrol cycles last 4–6 weeks due to the stress it places on the liver. A long cycle refers to:

  • Extending use to 8–10 weeks,

  • Cycling Oxymetholone at moderate doses,

  • Running it with strict health monitoring and liver support,

  • Often paired with injectable testosterone or other anabolics.

⚠️ Important: Long-term Oxymetholone use is not recommended for beginners or anyone without proper medical supervision.


πŸ“… Sample Oxymetholone Long Cycle

πŸ‹οΈ 8-Week Mass Building Stack

Compound Dosage
Oxymetholone (Anadrol) 25–50 mg/day (Weeks 1–8)
Testosterone Enanthate 500 mg/week (Weeks 1–12)
Deca Durabolin (optional) 300–400 mg/week (Weeks 1–10)
Aromasin or Arimidex As needed (for estrogen control)
TUDCA or NAC Daily (liver support)
Omega-3, CoQ10, Hawthorn Daily (heart and cholesterol)

πŸ“ˆ Expected Results from a Long Oxymetholone Cycle

With proper nutrition and training, a long Anadrol cycle can produce:

  • Massive size gains: 20–30+ lbs possible

  • Faster strength gains: Especially in compound lifts

  • Improved endurance and vascularity

  • Rapid pump effect from increased red blood cell production

However, water retention and temporary gains are common. A proper post-cycle therapy (PCT) is critical for maintaining muscle after the cycle ends.


⚠️ Risks & Side Effects of Extended Oxymetholone Use

While the rewards are impressive, the risks are real, especially on long cycles:

Side Effects Include:

  • Liver toxicity (Oxymetholone is a 17-alpha alkylated steroid)

  • Elevated blood pressure

  • Appetite suppression

  • Estrogen-related issues (bloat, gynecomastia)

  • Suppressed natural testosterone production

  • Cholesterol imbalance (decreased HDL, increased LDL)

πŸ’‘ Tip: Regular blood work is highly recommended during a long cycle.


🧠 How to Minimize Side Effects

Liver Protection

  • Use TUDCA, NAC, or Milk Thistle throughout the cycle.

  • Avoid alcohol and other liver-toxic compounds.

Estrogen Control

  • While Anadrol doesn’t convert to estrogen directly, it mimics estrogen-like effects.

  • Use Aromasin (Exemestane) or Arimidex to control water retention and prevent gyno.

Cardiovascular Support

  • Include Omega-3s, CoQ10, and monitor blood pressure weekly.

  • Cardio sessions 2–3x a week can help mitigate heart risks.


πŸ”„ Post Cycle Therapy (PCT) After a Long Cycle

Oxymetholone shuts down natural testosterone production quickly. Running a comprehensive PCT after your long cycle is non-negotiable.

PCT Protocol (Start Week 13):

Compound Dosage
Clomid 50/50/25/25 mg (Weeks 1–4)
Nolvadex 40/40/20/20 mg (Weeks 1–4)
TUDCA Continue for 2–4 weeks

🧬 Bonus Tip: Add natural test boosters like D-Aspartic Acid or ZMA during PCT for extra support.


❓ FAQ: Oxymetholone Long Cycle

Q: Is a long Oxymetholone cycle safe?
A: Not entirely. Even with liver support, extending Anadrol use raises risk. Only advanced users with health monitoring should consider it.

Q: Can I taper the dose down?
A: Yes. Some users start with 50 mg/day and taper to 25 mg/day near the end to ease the transition and reduce side effects.

Q: Is injectable Oxymetholone a better option for long cycles?
A: Injectable versions may reduce liver strain but come with sterility and sourcing concerns. They are not FDA-approved and often UG-sourced.

Q: What diet supports a long Anadrol cycle?
A: High-protein (1.2–1.5g/lb), calorie-surplus diet with complex carbs, healthy fats, and plenty of water (to manage bloat and blood pressure).


🏁 Final Thoughts: Is a Long Oxymetholone Cycle Worth It?

A long Oxymetholone cycle can offer incredible size and strength gains, but it comes with an increased burden on your liver, heart, and hormones.

βœ… Recommended For:

  • Experienced bodybuilders

  • Off-season bulking

  • Athletes with access to regular bloodwork

❌ Not Ideal For:

  • New users or beginners

  • People with pre-existing liver or heart conditions

  • Cutting cycles (due to water retention)

Approach with caution, plan your support and PCT in advance, and prioritize your health over ego lifting. When used wisely, Oxymetholone can be a game-changer in your bulking arsenal.

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